| Identification | Back Directory | [Name]
(+)-CBI-CDPI1 | [CAS]
128300-14-1 | [Synonyms]
(+)-CBI-CDPI1
Benzo[1,2-b:4,3-b']dipyrrole-3(2H)-carboxamide, 7-[[(8bR,9aS)-9,9a-dihydro-4-oxo-1H-benzo[e]cycloprop[c]indol-2(4H)-yl]carbonyl]-1,6-dihydro- (9CI) | [Molecular Formula]
C25H20N4O3 | [MDL Number]
MFCD32197302 | [MOL File]
128300-14-1.mol | [Molecular Weight]
424.45 |
| Hazard Information | Back Directory | [Uses]
(+)-CBI-CDPI1 is an enhanced functional analog of CC-1065. (+)-CBI-CDPI1 is a DNA alkylating agent. (+)-CBI-CDPI1 is an antibody agent conjugates (ADCs) toxin. | [IC 50]
Duocarmycins | [storage]
Store at -20°C | [References]
[1] Boger DL, et al. Molecular basis for sequence selective DNA alkylation by (+)- and ent-(-)-CC-1065 and related agents: alkylation site models that accommodate the offset AT-rich adenine N3 alkylation selectivity. Bioorg Med Chem. 1994 Feb;2(2):115-35. DOI:10.1016/s0968-0896(00)82007-6 |
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