| Identification | Back Directory | [Name]
Azeliragon HCl | [CAS]
1284150-65-7 | [Synonyms]
TTP488 HCl
Azeliragon HCl
Azeliragon HCl (TTP488
Azeliragon hydrochloride
Azeliragon dihydrochloride | [Molecular Formula]
C32H39Cl2N3O2 | [MDL Number]
MFCD33023403 | [MOL File]
1284150-65-7.mol | [Molecular Weight]
568.58 |
| Hazard Information | Back Directory | [Description]
Azeliragon, also known as TTP488 and PF-04494700, is a potent and orally active RAGE inhibitor. RAGE (receptor for advanced glycation endproducts) is a pattern recognition receptor, which affects the movement of amyloid, an Alzheimer's-associated protein, into the brain. In preclinical studies, azeliragon decreased brain amyloid in mice and improved their performance on behavior tests. Azeliragon is a promising agent for for Alzheimer's disease and cerebral amyloid angiopathy. | [Uses]
3-(4-(2-Butyl-1-(4-(4-chlorophenoxy)phenyl)-1H-imidazol-4-yl)phenoxy)-N,N-diethylpropan-1-amine Hyrochloride acts as a reagent in the preparation of imidazoles for the treatment of RAGE-mediated diseases and pharmacokinetics. |
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| Company Name: |
InvivoChem
|
| Tel: |
13549236410 |
| Website: |
https://www.invivochem.cn/ |
| Company Name: |
Biorbyt Ltd.
|
| Tel: |
+44 (0)1223 859 353 |
| Website: |
http://www.biorbyt.com |
|