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1286862-52-9

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1286862-52-9 Structure

1286862-52-9 Structure
IdentificationBack Directory
[Name]

XIE18-6
[CAS]

1286862-52-9
[Synonyms]

XIE186
XIE18-6
XIE18 6
[Molecular Formula]

C18H15NO6S
[MOL File]

1286862-52-9.mol
[Molecular Weight]

373.38
Hazard InformationBack Directory
[Description]

XIE18-6 is a novel INK4C inhibitor, specifically blocking the bioactivity of p18 protein and promoting human and murine hematopoietic stem cell ex vivo expansion.
[Uses]

XIE18-6 is a potent INK4C (p18) inhibitor. XIE18-6 shows potent bioactivity in hematopoietic stem cells (HSCs) expansion with an ED50 of 105.5 nM[1].
[References]

[1] Xiang-Qun Xie, et al. Discovery of novel INK4C small-molecule inhibitors to promote human and murine hematopoietic stem cell ex vivo expansion. Sci Rep. 2015 Dec 18:5:18115. DOI:10.1038/srep18115
Spectrum DetailBack Directory
[Spectrum Detail]

XIE18-6(1286862-52-9)1HNMR
1286862-52-9 suppliers list
Company Name: Jinan Jiuli Biotechnology Co. , Ltd.  
Telephone: 15865264761
Website: www.chemicalbook.com/ShowSupplierProductsList89365/0_EN.htm
Company Name: TargetMol Chemicals Inc.  
Telephone: 15002134094
Website: https://www.targetmol.cn/
Company Name: Shaoguan Qicheng Biotechnology Co., Ltd  
Telephone: 18122215013
Website: https://www.chemicalbook.com/ShowSupplierProductsList1488808/0_EN.htm
Company Name: Shanghai Amole Biotechnology Co., Ltd.  
Telephone: 13370042665 18916960931
Website: www.amole.com.cn/
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