| Identification | Back Directory | [Name]
(5E)-2-sulfanylidene-5-[[5-[3-(trifluoromethyl)phenyl]furan-2-yl]methylidene]-1,3-thiazolidin-4-one | [CAS]
1287652-03-2 | [Synonyms]
4-Thiazolidinone, 2-thioxo-5-[[5-[3-(trifluoromethyl)phenyl]-2-furanyl]methylene]-, (5E)-
(5E)-2-sulfanylidene-5-[[5-[3-(trifluoromethyl)phenyl]furan-2-yl]methylidene]-1,3-thiazolidin-4-one | [Molecular Formula]
C15H8F3NO2S2 | [MOL File]
1287652-03-2.mol | [Molecular Weight]
355.35 |
| Hazard Information | Back Directory | [Uses]
CCR-11 is an antibacterial agent. CCR-11 can inhibit the proliferation of B. subtilis cells with an IC50 value of 1.2 μM. CCR-11 inhibits HeLa cell proliferation with an IC50 value of 18.1 μM. CCR-11 inhibits bacterial cytokinesis by inhibiting FtsZ assembly. CCR-11 can be used for the research of FtsZ-targeted antibacterial agents[1]. | [References]
[1] Singh P, et al. A rhodanine derivative CCR-11 inhibits bacterial proliferation by inhibiting the assembly and GTPase activity of FtsZ. Biochemistry. 2012 Jul 10;51(27):5434-42. DOI:10.1021/bi201813u |
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