| Hazard Information | Back Directory | [Description]
SEN461 is a Wnt inhibitor/Axin stabilizer. | [Uses]
SEN461 is a potent and orally active Wnt pathway inhibitor. SEN461 shows effective anti-tumor activity and can be used for GBM research[1]. | [References]
[1] Nencini, A, et al. Structure–activity relationship and properties optimization of a series of Quinazoline-2,4-diones as inhibitors of the canonical Wnt pathway. European Journal of Medicinal Chemistry, 95, 526–545. DOI:10.1016/j.ejmech.2015.03.055 |
|
|