| Chemical Properties | Back Directory | [density ]
1.243±0.14 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted) | [form ]
Solid | [pka]
8.465±0.15(predicted) | [color ]
Off-white to yellow |
| Hazard Information | Back Directory | [Uses]
LSD1-IN-30 (compound 3) is a potent inhibitor of lysine-specific demethylase 1 (LSD1), with the IC50 value of 0.291 μM[1]. | [IC 50]
LSD1: 0.291 μM (IC50) | [References]
[1] Venkataswamy Sorna, et al. High-Throughput Virtual Screening Identifies Novel N′?(1-Phenylethylidene)-benzohydrazides as Potent, Specific, and Reversible LSD1 Inhibitors. J Med Chem
. 2013 Dec 12;56(23):9496-508. DOI:10.1021/jm400870h |
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