| Identification | Back Directory | [Name]
viridicatin | [CAS]
129-24-8 | [Synonyms]
viridicatin
2,3-Dihydroxy-4-phenylquinoline
3-hydroxy-4-phenylquinolin-2(1H)-one
2(1H)-Quinolinone, 3-hydroxy-4-phenyl- | [Molecular Formula]
C15H11NO2 | [MDL Number]
MFCD00965001 | [MOL File]
129-24-8.mol | [Molecular Weight]
237.25 |
| Chemical Properties | Back Directory | [Melting point ]
268° | [storage temp. ]
Store at -20°C | [solubility ]
DMF: soluble; DMSO: soluble; Ethanol: moderately soluble; Methanol: moderately soluble | [form ]
Off-white to brown solid. |
| Hazard Information | Back Directory | [Uses]
Viridicatin is a fungal metabolite produced by several species of Penicillium and formed by the rearrangement of the benzodiazepine, cyclopenin. Viridicatin exhibits potent selective activity against Mycobacterium tuberculosis, but is inactive against most other bacteria. | [Uses]
Viridicatin is a?Penicillium?metabolite active against?Mycobacterium tuberculosis. Isolated from deep-sea Penicillium griseofulvum alleviates anaphylaxis and has anti-?allergic properties. | [Definition]
ChEBI: Viridicatin is a hydroxyquinolone that is 3-hydroxyuinolin-2(1H)-one which is substituted at position 4 by a phenyl groups. Isolated from the mycelium of several Penicillium species, it exhibits strong antibiotic activity against M. tuberculosis and also against B. subtilis, S. aureus and S. cerevisiae. It has a role as an antibacterial agent, a Penicillium metabolite, a marine metabolite and an Aspergillus metabolite. It is a conjugate acid of a viridicatin(1-). | [IC 50]
Microbial Metabolite |
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