| Identification | Back Directory | [Name]
CLENBUTEROL D9 | [CAS]
129138-58-5 | [Synonyms]
Clenbuterol-D9
(±)-Clenbuterol D9 (trimethyl D9)
1-(4-Amino-3,5-dichlorophenyl)-2-(tert-butyl-d9-amino)ethanol
4-Amino-α-(tert-butyl-d9-aminomethyl)-3,5-dichlorobenzyl alcohol
4-Amino-3,5-dichloro-α-[[(1,1-dimethylethyl-d9)amino]methyl]benzenemethanol
4-amino-3,5-dichloro-.α.-[[[1,1-di(methyl-d3)ethyl-2,2,2-d3]amino]methyl]Benzenemethanol
4-amino-3,5-dichloro-.alpha.-[[[1,1-di(methyl-d3)ethyl-2,2,2-d3]amino]methyl]Benzenemethanol
4-Amino-α-(tert-butyl-d9-aminomethyl)-3,5-dichlorobenzyl alcohol, 1-(4-Amino-3,5-dichlorophenyl)-2-(tert-butyl-d9-amino)ethanol | [EINECS(EC#)]
253-366-0 | [Molecular Formula]
C12H9Cl2D9N2O | [MDL Number]
MFCD01863370 | [MOL File]
129138-58-5.mol | [Molecular Weight]
286.248 |
| Questions And Answer | Back Directory | [Synthesis]
In a dry reaction flask, the hydrochloride salt of the CLENBUTEROL D9 precursor compound ketone was added. Then, an aqueous solution of sodium hydroxide and the reducing agent sodium borohydride were slowly added to the reaction flask. The resulting reaction mixture was stirred overnight at 0°C. The reaction progress was monitored by TLC. After the reaction was complete, ethyl acetate and water were added, and the organic layer was separated. The aqueous layer was extracted twice with ethyl acetate. All organic layers were combined, dried with anhydrous magnesium sulfate, and the drying agent was removed by filtration. The filtrate was then concentrated under vacuum to obtain the target drug molecule, CLENBUTEROL D9.  Figure: CLENBUTEROL D9 Synthetic Route |
| Chemical Properties | Back Directory | [Appearance]
White Crystalline Solid | [Melting point ]
112-115°C | [storage temp. ]
Hygroscopic, -20°C Freezer, Under Inert Atmosphere | [solubility ]
DMSO (Slightly), Methanol (Slightly) | [form ]
Solid | [color ]
White to Off-White | [Stability:]
Store in Freezer | [InChI]
InChI=1S/C12H18Cl2N2O/c1-12(2,3)16-6-10(17)7-4-8(13)11(15)9(14)5-7/h4-5,10,16-17H,6,15H2,1-3H3/i1D3,2D3,3D3 | [InChIKey]
STJMRWALKKWQGH-GQALSZNTSA-N | [SMILES]
C(C([2H])([2H])[2H])(C([2H])([2H])[2H])(C([2H])([2H])[2H])NCC(O)C1C=C(C(N)=C(Cl)C=1)Cl |
| Hazard Information | Back Directory | [Chemical Properties]
White Crystalline Solid | [Uses]
A -Agonist which can be used as a growth promoter in farm animals | [Uses]
A β-Agonist which can be used as a growth promoter in farm animals. |
| Safety Data | Back Directory | [Hazard Codes ]
T,Xn | [Risk Statements ]
25-22 | [Safety Statements ]
22-36/37/39-45 | [RIDADR ]
UN2811 6.1/PG 3 | [WGK Germany ]
WGK 3 | [HS Code ]
28459000 | [Storage Class]
11 - Combustible Solids | [Hazard Classifications]
Acute Tox. 4 Oral |
|
| Company Name: |
J & K SCIENTIFIC LTD.
|
| Telephone: |
18210857532 18210857532 |
| Website: |
https://www.jkchemical.com |
| Company Name: |
TOSUN PHARM
|
| Telephone: |
020-66392521-118 18922260391 |
| Website: |
www.toref.cn/ |
|