| Identification | Back Directory | [Name]
DIGOXIGENIN NHS-ESTER | [CAS]
129273-26-3 | [Synonyms]
5'-Digoxin Phosphoramidite
Digoxigenin NHS-ester >=80% (HPLC)
-aminocaproic acid-N-hydroxysuccinimide ester
ω-(Digoxigenin-3-0-acetamido)caproic acid N-hydroxysuccinimide ester
n-hydroxysuccinimidyldigoxigenin-3-o-methylcarbonyl-epsilon-aminocaproate
Digoxigenin-3-O-methylcarbonyl-ε-aminocaproic acid-N-hydroxysuccinimide ester
(3β,5β,12β)-3-[2-[[6-[(2,5-Dioxo-1-pyrrolidinyl)oxy]-6-oxohexyl]amino]-2-oxoethoxy]-12,14-dihydroxycard-20(22)-enolide | [Molecular Formula]
C35H50N2O10 | [MDL Number]
MFCD02093394 | [MOL File]
129273-26-3.mol | [Molecular Weight]
658.784 |
| Chemical Properties | Back Directory | [density ]
1.33±0.1 g/cm3(Predicted) | [storage temp. ]
-20°C | [solubility ]
DMF: soluble | [form ]
powder | [pka]
14.43±0.70(Predicted) | [color ]
White to off-white | [Stability:]
Moisture Sensitive | [InChIKey]
KHNDABJZSPPYLE-BPYGFDTQNA-N | [SMILES]
[H][C@]12CC[C@]3([H])[C@]([H])(C[C@@H](O)[C@]4(C)[C@H](CC[C@]34O)C5=CC(=O)OC5)[C@@]1(C)CC[C@@H](C2)OCC(=O)NCCCCCC(=O)ON6C(=O)CCC6=O |
| Hazard Information | Back Directory | [Uses]
Digoxigenin NHS-ester is an activated ester which reacts with amino groups under mild conditions, attaching the digoxigenin moiety to proteins or 5′-amino substituted oligonucleotides Digoxigenin labeling is used to immuno-tag molecules for detection using anti-digoxigenin antibodies with high affinities and specificity. | [Uses]
Digoxigenin-3-O-methylcarbonyl-ε-aminocaproic acid-N-hydroxysuccinimide ester has been used to label the sequence (III) for the linker molecule sequence (VIII). | [General Description]
Chemical reagent for the labeling of proteins and oligonucleotides. One reactive group is able to interact with NH2-groups (of proteins or oligonucleotides), another reactive group (Digoxigenin) reacts with Anti-Digoxigenin and thus can be detected.
| [Biochem/physiol Actions]
Digoxigenin, a non-radioactive immune-tag is mainly used for labeling proteins and in situ?hybridization. |
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| Company Name: |
Sonia Organics
|
| Tel: |
+91-9538454135 |
| Website: |
www.soniaorganics.in |
| Company Name: |
Sigma-Aldrich
|
| Tel: |
021-61415566 800-8193336 |
| Website: |
https://www.sigmaaldrich.cn |
| Company Name: |
Energy Chemical
|
| Tel: |
021-58432009 400-005-6266 |
| Website: |
http://www.energy-chemical.com |
|