| Identification | Back Directory | [Name]
Pierreione B | [CAS]
1292766-21-2 | [Synonyms]
Pierreione B
7-[4-[(2R)-2,3-Dihydroxy-3-methylbutoxy]-3-methoxyphenyl]-2,2-dimethyl-2H,6H-benzo[1,2-b:5,4-b']dipyran-6-one
2H,6H-Benzo[1,2-b:5,4-b']dipyran-6-one, 7-[4-[(2R)-2,3-dihydroxy-3-methylbutoxy]-3-methoxyphenyl]-2,2-dimethyl- | [Molecular Formula]
C26H28O7 | [MOL File]
1292766-21-2.mol | [Molecular Weight]
452.5 |
| Hazard Information | Back Directory | [Uses]
Pierreione B is a pyranoisoflavone, that can be isolated from the leaves and twigs of Antheroporum pierrei. Pierreione B demonstrates solid tumor selectivity with minimal cytotoxicity[1]. | [Definition]
ChEBI: Pierreione B is a methoxyisoflavone that is isoflavone substituted by a methoxy group at position 3', a 2R,3-dihydroxy-3-methylbutoxyl group at position 4' and a dimethylpyran ring fused across positions 6 and 7. Isolated from Antheroporum pierrei, it exhibits antineoplastic activity. It has a role as a metabolite, a plant metabolite and an antineoplastic agent. | [References]
[1] Gao S, et al. Pierreiones A-D, solid tumor selective pyranoisoflavones and other cytotoxic constituents from Antheroporum pierrei. J Nat Prod. 2011 Apr 25;74(4):852-6. DOI:10.1021/np100763p |
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