| Identification | Back Directory | [Name]
5,6-DCI-CBIMF SODIUM SALT | [CAS]
129693-10-3 | [Synonyms]
5,6-DCl-cBIMP
5,6-DCI-CBIMP, NA
CDRBMP SODIUM SALT
5,6-DCI-CBIMF SODIUM SALT
1H-Benzimidazole, 5,6-dichloro-1-(3,5-O-phosphinico-β-D-ribofuranosyl)-
5,6-Dichloro-1-B-D-ribofuranosylbenzimidazole-3'',5''-cyclic monophosphoric a
5,6-dichlorobenzimidazoleriboside-3’,5’-cyclicmonophosphate(5,6-dcl-cbimp),sodium
5,6-DICHLORO-1-BETA-D-RIBOFURANOSYLBENZIMIDAZOLE-3',5'-CYCLIC MONOPHOSPHATE SODIUM SALT | [Molecular Formula]
C12H11Cl2N2O6P | [MDL Number]
MFCD03453546 | [MOL File]
129693-10-3.mol | [Molecular Weight]
381.11 |
| Hazard Information | Back Directory | [Uses]
5,6-DCl-cBIMP, a cyclic adenosine monophosphate analog, can act as an agonist of PDE2 and significantly enhance the cAMP and cGMP hydrolytic activities of PDE2[1][2]. | [References]
[1] McMartin L, et al. Functional analysis of desensitization of the β‐adrenoceptor signalling pathway in rat cardiac tissues following chronic isoprenaline infusion[J]. British journal of pharmacology, 1999, 127(4): 1012-1020. DOI:10.1038/sj.bjp.0702618
[2] J?ger R, et al. Activation of PDE2 and PDE5 by specific GAF ligands: delayed activation of PDE5[J]. British journal of pharmacology, 2010, 161(7): 1645-1660. DOI:10.1111/j.1476-5381.2010.00977.x |
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