| Identification | Back Directory | [Name]
1,4-Naphthalenedione, 2-(acetyloxy)-3-[trans-4-(4-chlorophenyl)cyclohexyl]-1,4-dihydro- | [CAS]
129700-44-3 | [Synonyms]
1,4-Naphthalenedione, 2-(acetyloxy)-3-[trans-4-(4-chlorophenyl)cyclohexyl]-1,4-dihydro- | [Molecular Formula]
C24H21ClO4 | [MOL File]
129700-44-3.mol | [Molecular Weight]
408.87 |
| Hazard Information | Back Directory | [Uses]
Ac-Atovaquone is a potent cytochrome bc1 inhibitor and also is an ester-linked acetyl derivative of atovaquone (HY-13832). Ac-Atovaquone has the potential for the research of malaria[1][1][2]. | [References]
[1] Siqueira-Neto JL, et al. Antimalarial drug discovery: progress and approaches. Nat Rev Drug Discov. 2023 Oct;22(10):807-826. doi: 10.1038/s41573-023-00772-9. Epub 2023 Aug 31. Erratum in: Nat Rev Drug Discov. 2024 Nov;23(11):880.
[2] El Gaaloul M, et al. Chemoprevention of malaria with long-acting oral and injectable drugs: an updated target product profile. Malar J. 2024 Oct 18;23(1):315. DOI:10.1186/s12936-024-05128-1 |
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