| Identification | Back Directory | [Name]
ORM-15341 | [CAS]
1297537-33-7 | [Synonyms]
ORM-15341
Ketodarolutamide
ORM-15341(Ketodarolutamide)
(S)-5-acetyl-N-(1-(3-(3-chloro-4-cyanophenyl)-1H-pyrazol-1-yl)propan-2-yl)-1H-pyrazole-3-carboxamide
(S)-3-acetyl-N-(1-(3-(3-chloro-4-cyano-phenyl)-1H-pyrazol-1-yl)propan-2-yl)-1H-pyrazole-5-carboxamide
5-Acetyl-N-[(1S)-2-[3-(3-chloro-4-cyanophenyl)-1H-pyrazol-1-yl]-1-methylethyl]-1H-Pyrazole-3-carboxamide
1H-Pyrazole-3-carboxamide, 5-acetyl-N-[(1S)-2-[3-(3-chloro-4-cyanophenyl)-1H-pyrazol-1-yl]-1-methylethyl]- | [Molecular Formula]
C19H17ClN6O2 | [MDL Number]
MFCD29472275 | [MOL File]
1297537-33-7.mol | [Molecular Weight]
396.83 |
| Chemical Properties | Back Directory | [Melting point ]
210 - 212?C | [Boiling point ]
714.7±60.0 °C(Predicted) | [density ]
1.41±0.1 g/cm3(Predicted) | [storage temp. ]
-20°C Freezer, Under inert atmosphere | [solubility ]
DMSO (Slightly), Methanol (Slightly, Heated, Sonicated) | [form ]
Solid | [pka]
8.70±0.10(Predicted) | [color ]
White to Off-White | [InChI]
InChI=1S/C19H17ClN6O2/c1-11(22-19(28)18-8-17(12(2)27)23-24-18)10-26-6-5-16(25-26)13-3-4-14(9-21)15(20)7-13/h3-8,11H,10H2,1-2H3,(H,22,28)(H,23,24)/t11-/m0/s1 | [InChIKey]
GMBPVBVTPBWIKC-NSHDSACASA-N | [SMILES]
N1C(C(C)=O)=CC(C(N[C@@H](C)CN2C=CC(C3=CC=C(C#N)C(Cl)=C3)=N2)=O)=N1 |
| Hazard Information | Back Directory | [Uses]
ORM-15341 is a metabolite of Darolutamide. Darolutamide is a potent androgen receptor antagonist with strong efficacy in prostate cancer models. | [storage]
Store at -20°C |
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