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129960-90-3

129960-90-3 Structure

129960-90-3 Structure
IdentificationBack Directory
[Name]

3-azidotyrosine
[CAS]

129960-90-3
[Synonyms]

3-azidotyrosine
H-L-Tyr(3-N3)-OH
3-azido-L-tyrosine
(2S)-2-Amino-3-(3-azido-4-hydroxyphenyl)propanoic acid
[Molecular Formula]

C9H10N4O3
[MDL Number]

MFCD19105590
[MOL File]

129960-90-3.mol
[Molecular Weight]

222.2
Hazard InformationBack Directory
[Uses]

H-L-Tyr(3-N3)-OH is a click chemistry reagent containing an azide[1]. H-L-Tyr(3-N3)-OH is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
[References]

[1] Yokogawa T, et al. Incorporation of 3-azidotyrosine into proteins through engineering yeast tyrosyl-tRNA synthetase and its application to site-selective protein modification. Methods Mol Biol. 2010;607:227-42. DOI:10.1007/978-1-60327-331-2_19
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