| Identification | Back Directory | [Name]
2-Benzofurancarboxamide, N-[4-[4-(2,3-dichlorophenyl)-1-piperazinyl]-3-fluorobutyl]- | [CAS]
1301178-83-5 | [Synonyms]
BAK266
BAK2-66
BAK2 66
2-Benzofurancarboxamide, N-[4-[4-(2,3-dichlorophenyl)-1-piperazinyl]-3-fluorobutyl]- | [Molecular Formula]
C23H24Cl2FN3O2 | [MOL File]
1301178-83-5.mol | [Molecular Weight]
464.36 |
| Hazard Information | Back Directory | [Description]
BAK2-66 is a selective dopamine D3 receptor antagonist. | [Uses]
(±)-BAK2-66 is a selectivity dopamine D3 receptor antagonist with theKi values of 1nM and 960 nM for D3R and D2R, respectively. (±)-BAK2-66 can be used for study in animal models of addiction[1]. | [References]
[1] Kumar V, et al. Chiral Resolution and Serendipitous Fluorination Reaction for the Selective Dopamine D3 Receptor Antagonist BAK2-66. ACS Med Chem Lett. 2014;5(6):647-651. Published 2014 Mar 24. DOI:10.1021/ml500006v |
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