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130154-64-2

130154-64-2 Structure

130154-64-2 Structure
IdentificationBack Directory
[Name]

H-TRP-TRP-GLY-LYS-LYS-TYR-ARG-ALA-SER-LYS-LEU-GLY-LEU-ALA-ARG-OH
[CAS]

130154-64-2
[Synonyms]

WWGKKYRASKLGLAR
[TRP63,64]-C3A (63-77)
(TRP63,TRP64)-C3A (63-77)
TRP-TRP-GLY-LYS-LYS-TYR-ARG-ALA-SER-LYS-LEU-GLY-LEU-ALA-ARG
H-TRP-TRP-GLY-LYS-LYS-TYR-ARG-ALA-SER-LYS-LEU-GLY-LEU-ALA-ARG-OH
[Molecular Formula]

C86H134N26O18
[MDL Number]

MFCD00236897
[MOL File]

130154-64-2.mol
[Molecular Weight]

1820.15
Chemical PropertiesBack Directory
[Appearance]

White powder
[density ]

1.43±0.1 g/cm3(Predicted)
[storage temp. ]

-15°C
[pka]

3.34±0.10(Predicted)
[Sequence]

Trp-Trp-Gly-Lys-Lys-Tyr-Arg-Ala-Ser-Lys-Leu-Gly-Leu-Ala-Arg
Hazard InformationBack Directory
[Chemical Properties]

White powder
[Uses]

(Trp63,Trp64)?-?C3a(63-77) is a C3a synthetic analogue peptide, which exhibits Ca2+ stimulating efficacy in human neutrophils and hC3aR or mC3aR expressing RBL-2H3 cells with EC50 of 9.5, 2.0 and 0.8 nM, respectively[1].
[References]

[1] Ames RS, et al., Evidence that the receptor for C4a is distinct from the C3a receptor. Immunopharmacology. 1997 Dec;38(1-2):87-92. DOI:10.1016/s0162-3109(97)00079-9
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