| Identification | Back Directory | [Name]
CCG 2046 | [CAS]
13017-69-1 | [Synonyms]
CCG 2046
3-Methyl-3-propyl-1,1,2,2-cyclopropanetetracarbonitrile
1,1,2,2-Cyclopropanetetracarbonitrile, 3-methyl-3-propyl- | [Molecular Formula]
C11H10N4 | [MDL Number]
MFCD00182400 | [MOL File]
13017-69-1.mol | [Molecular Weight]
198.22 |
| Chemical Properties | Back Directory | [Boiling point ]
467.4±45.0 °C(Predicted) | [density ]
1.17±0.1 g/cm3(Predicted) | [storage temp. ]
Desiccate at +4°C | [solubility ]
<19.82mg/ml in DMSO |
| Hazard Information | Back Directory | [Uses]
CCG-2046 is a RGS4 inhibitor with an IC50 of 4.3 μM against RGS4-Gαo interaction signal[1]. | [Biological Activity]
Inhibitor of regulator of G-protein signaling 4 (RGS4). Reduces the RGS4-G α o protein-protein interaction signal. | [IC 50]
RGS4: 4.3 μM (IC50) | [storage]
Store at -20°C | [References]
[1] Roman DL, et al. Identification of small-molecule inhibitors of RGS4 using a high-throughput flow cytometry protein interaction assay. Mol Pharmacol. 2007 Jan;71(1):169-75. DOI:10.1124/mol.106.028670 |
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