| Identification | Back Directory | [Name]
1-[3-(3,4-dimethoxyphenyl)prop-2-enoyl]piperidin-2-one | [CAS]
130263-10-4 | [Synonyms]
Demethoxypiplartine
3'-DeMethoxypiplartine
3'-Demethoxypiplartine/Demethoxypiplartine
N-(3,4-Dimethoxy-(E)-cinnamoyl)-delta3-pyridin-2-one
1-[3-(3,4-dimethoxyphenyl)prop-2-enoyl]piperidin-2-one
(E)-1-(3-(3,4-dimethoxyphenyl)acryloyl)-5,6-dihydropyridin-2(1H)-one
2(1H)-Pyridinone, 1-[3-(3,4-dimethoxyphenyl)-1-oxo-2-propenyl]-5,6-dihydro-, (E)- (9CI) | [Molecular Formula]
C16H17NO4 | [MDL Number]
MFCD26406197 | [MOL File]
130263-10-4.mol | [Molecular Weight]
287.31 |
| Chemical Properties | Back Directory | [Melting point ]
116-117℃ (methanol ) | [Boiling point ]
449.6±45.0 °C(Predicted) | [density ]
1.220±0.06 g/cm3(Predicted) | [pka]
-1.87±0.20(Predicted) |
| Hazard Information | Back Directory | [Uses]
Demethoxypiplartine is an amide alkaloids which can be isolated from Piper flaviflorum and Piper sarmentosum. Demethoxypiplartine has antifungal activity against Cryptococcus neoformans with the IC50 of 18.1 μg/mL[1]. | [References]
[1] Shi YN, et al. Antifungal Amide Alkaloids from the Aerial Parts of Piper flaviflorum and Piper sarmentosum. Planta Med. 2017 Jan;83(1-02):143-150. DOI:10.1055/s-0042-109778 |
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