130714-47-5

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130714-47-5 Structure

Identification	Back Directory
[Name] SDZWAG994
[CAS] 130714-47-5
[Synonyms] WAG 994 SDZWAG994 N-Cyclohexyl-2'-O-methyladenosine N(6)-cyclohexyl-2-O-methyladenosine Adenosine, N-cyclohexyl-2'-O-methyl-
[Molecular Formula] C17H25N5O4
[MOL File] 130714-47-5.mol
[Molecular Weight] 363.41

Chemical Properties	Back Directory
[storage temp. ] Desiccate at +4°C
[solubility ] Soluble to 100 mM in 1.1eq. NaOH and to 100 mM in DMSO
[form ] Powder

Safety Data	Back Directory
[Symbol(GHS) ] GHS07
[Signal word ] Warning
[Hazard statements ] H302-H315-H319-H335
[Precautionary statements ] P261-P305+P351+P338

Hazard Information	Back Directory
[Uses] Adenosine receptors are potential therapeutic targets for cerebral and cardiac ischaemic diseases, sleep disorders, immune and inflammatory disorders and cancer. N-Cyclohexyl-2''-O-methyladenosine is an inhibitor of adenosine deaminase-induced lipolysis and a selective adenosine A1-R agonist.
[Biological Activity] Potent and selective A 1 adenosine receptor agonist (K i values are 23, > 10000 and 25000 nM for A 1 , A 2A and A 2B receptors respectively). Causes a sustained fall in blood pressure and heart rate in spontaneous hypertensive rats and inhibits adenosine deaminase-stimulated lipolysis in rat adipocytes (K i = 8 nM).
[storage] Store at -20°C

Spectrum Detail	Back Directory
[Spectrum Detail] SDZWAG994(130714-47-5)¹HNMR

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