| Identification | Back Directory | [Name]
m-PEG6-Ms | [CAS]
130955-38-3 | [Synonyms]
m-PEG6-Ms
2,5,8,11,14-Pentaoxahexadecan-16-ol, 16-methanesulfonate | [Molecular Formula]
C12H26O8S | [MDL Number]
MFCD31693723 | [MOL File]
130955-38-3.mol | [Molecular Weight]
330.39 |
| Hazard Information | Back Directory | [Description]
m-PEG6-Ms is a PEG linker containing a mesyl group. The mesyl group is a good leaving group for nucleophilic substitution reactions. The hydrophilic PEG spacer increases solubility in aqueous media. The water solubility properties of the PEG chain are enhanced with longer PEG chains. | [Uses]
m-PEG5-MS is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. m-PEG5-MS is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. | [IC 50]
Cleavable Linker; PEGs | [References]
[1] Sanxing Sun, et al. Triazolotriazine derivatives as a2a receptor antagonists. WO2020002969A1. |
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