| Identification | Back Directory | [Name]
Mps-BAY1 | [CAS]
1309593-24-5 | [Synonyms]
Mps-BAY1
Benzeneacetamide, N-[4-[2-[(2-cyanophenyl)amino][1,2,4]triazolo[1,5-a]pyridin-6-yl]phenyl]- | [Molecular Formula]
C27H20N6O | [MOL File]
1309593-24-5.mol | [Molecular Weight]
444.49 |
| Hazard Information | Back Directory | [Uses]
Mps-BAY1 is an MPS1 inhibitor with anticancer activity. Mps-BAY1 inhibits cell proliferation and induces apoptosis by activating mitotic catastrophe in cancer cells, generating global aneuploidy and polyploidy. Mps-BAY1 can be used in the study of colorectal cancer and cervical cancer[1]. | [References]
[1] Jemaa, et al. "Characterization of novel MPS1 inhibitors with preclinical anticancer activity." Cell Death & Differentiation 20.11 (2013): 1532-1545. DOI:10.1038/cdd.2013.105 |
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