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Neuroprotective agent 3 (Compound 21a) is an antioxidant that exhibits neuroprotective effects. Neuroprotective agent 3 significantly increases neuronal viability and induces neuroprotection, as well as improves neurological deficit scores in an in vivo model of transient cerebral ischemia[1]. | [References]
[1] Escobar-Peso A, et al. Synthesis, antioxidant and neuroprotective analysis of diversely functionalized α-aryl-N-alkyl nitrones as potential agents for ischemic stroke therapy[J]. European Journal of Medicinal Chemistry, 2024: 116133. DOI:10.1016/j.ejmech.2024.116133 |
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