| Identification | Back Directory | [Name]
H-VAL-ALA-PRO-SER-ASP-SER-ILE-GLN-ALA-GLU-GLU-TRP-TYR-PHE-GLY-LYS-ILE-THR-ARG-ARG-GLU-OH | [CAS]
131023-24-0 | [Synonyms]
PEPTIDE A
PP60V-SRC (137-157)
P60 V-SRC (137-157)
VAPSDSIQAEEWYFGKITRRE
P60V-SRC 137-157 INHIBITOR PEPTIDE
Peptide A (Tyrosine Kinase Inhibitor)
TYROSINE-SPECIFIC PROTEIN KINASE INHIBITOR
VAL-ALA-PRO-SER-ASP-SER-ILE-GLN-ALA-GLU-GLU-TRP-TYR-PHE-GLY-LYS-ILE-THR-ARG-ARG-GLU
H-VAL-ALA-PRO-SER-ASP-SER-ILE-GLN-ALA-GLU-GLU-TRP-TYR-PHE-GLY-LYS-ILE-THR-ARG-ARG-GLU-OH
L-Glutamic acid, L-valyl-L-alanyl-L-prolyl-L-seryl-L-α-aspartyl-L-seryl-L-isoleucyl-L-glutaminyl-L-alanyl-L-α-glutamyl-L-α-glutamyl-L-tryptophyl-L-tyrosyl-L-phenylalanylglycyl-L-lysyl-L-isoleucyl-L-threonyl-L-arginyl-L-arginyl- | [Molecular Formula]
C111H168N30O35 | [MDL Number]
MFCD00168134 | [MOL File]
131023-24-0.mol | [Molecular Weight]
2482.7 |
| Hazard Information | Back Directory | [Uses]
P60v-src(137-157) is a synthetic peptide that inhibits the tyrosine kinase activity of p60v-src (IC50: 7.5 μM)[1][2]. | [References]
[1] Sato K, et al. A synthetic peptide corresponding to residues 137 to 157 of p60v-src inhibits tyrosine-specific protein kinases. Biochem Biophys Res Commun. 1990 Sep 28;171(3):1152-9. DOI:10.1016/0006-291x(90)90805-w
[2] Wijetunge S, et al. pp60c-src increases voltage-operated calcium channel currents in vascular smooth muscle cells. Biochem Biophys Res Commun. 1995 Dec 26;217(3):1039-44. DOI:10.1006/bbrc.1995.2874 |
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