| Identification | Back Directory | [Name]
CHOLERA TOXIN B SUBUNIT | [CAS]
131096-89-4 | [Synonyms]
CTxB
abs80001
CHOLERA TOXIN B SUBUNIT
Cholera Toxin B subunit-FITC
Cholera toxin subunit B(CTB)
Cholera Toxin B Subunit (CTB)
VIBRIO CHOLERAE TOXIN B SUBUNIT
cholera toxin B subunit from*vibrio cholerae
CHOLERA TOXIN B SUBUNIT (LOW SALT) FORMU LATION OF CHOLER
CHOLERA TOXIN, B SUBUNIT, VIBRIO CHOLERAE, TYPE INABA 569B
CHOLERA TOXIN B SUBUNIT VIBRIO CHOLERAE, PEROXIDASE CONJUGATE | [MDL Number]
MFCD00130778 |
| Chemical Properties | Back Directory | [storage temp. ]
-20°C | [solubility ]
H2O: 10 mg/mL, soluble
| [form ]
solid
| [color ]
white
| [Water Solubility ]
H2O: soluble 11mg/mL | [Specific Activity]
(Binds to GM1 ganglioside. The binding EC50 is lower than 1 ug/ml) | [InChI]
1S/C16H13ClF3NO2/c1-2-23-14-6-4-3-5-11(14)15(22)21-10-7-8-13(17)12(9-10)16(18,19)20/h3-9H,2H2,1H3,(H,21,22) | [InChIKey]
YDXZSNHARVUYNM-UHFFFAOYSA-N | [SMILES]
CCOc1ccccc1C(=O)Nc2ccc(Cl)c(c2)C(F)(F)F |
| Hazard Information | Back Directory | [Uses]
Cholera Toxin B subunit has been used:
- for macrophage stimulation and i.p. injection in a study to determine the endotoxin sensitivity of Caspase-4.
- in transganglionic and retrograde tract-tracing method combined with dual-immunofluorescence histochemistry of adult rat Vmes neuron cells.
| [General Description]
The advantage of this product over the native CTXB is that it has no traces of Vibrio cholera, and no contamination of the highly toxic Cholera toxin A subunit. This product is expressed in human HEK 293 cells as a C-terminally his-tagged protein with a calculated molecular mass of 13 kDa (amino acids Thr22-Asn124). | [Biochem/physiol Actions]
Cholera Toxin B subunit stimulates both systemic and mucosal antibody production in animals and humans. CTB functions as an oral subunit vaccine for cholera, which is associated with acute watery diarrhoea. |
|
| Company Name: |
T&W GROUP
|
| Tel: |
021-61551611 13296011611 |
| Website: |
www.trustwe.com/ |
| Company Name: |
Sigma-Aldrich
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| Tel: |
021-61415566 800-8193336 |
| Website: |
https://www.sigmaaldrich.cn |
| Company Name: |
Puripharm Co., Ltd.
|
| Tel: |
0572-2745768-1 13167223168 |
| Website: |
http://www.puriactives.com/ |
| Company Name: |
Merck KGaA
|
| Tel: |
21-20338288 |
| Website: |
www.sigmaaldrich.cn |
|