| Identification | Back Directory | [Name]
Scutebarbatine W | [CAS]
1312716-25-8 | [Synonyms]
Scutehenanine B
Scutebarbatine W
3-Pyridinecarboxylic acid, (3R,4'aR,5'S,6'R,6'aR,10'R,10'aS,10'bR)-10'-(benzoyloxy)-1',2',4'a,5',6',6'a,9',10',10'a,10'b-decahydro-5'-hydroxy-4'a,6'a,7',10'b-tetramethyl-5-oxospiro[furan-3(2H),3'-[3H]naphtho[2,1-b]pyran]-6'-yl ester | [Molecular Formula]
C33H37NO8 | [MDL Number]
MFCD20274623 | [MOL File]
1312716-25-8.mol | [Molecular Weight]
575.66 |
| Hazard Information | Back Directory | [Uses]
Scutebarbatine W is a 13-spiro subtype neo-clerodane diterpenoid. Scutebarbatine W inhibits NO production with an IC50 value of 34.7 μM[1][2]. | [References]
[1] Wang F, et al. Scutebarbatines W-Z, new neo-clerodane diterpenoids from Scutellaria barbata and structure revision of a series of 13-spiro neo-clerodanes. Chem Pharm Bull (Tokyo). 2010 Sep;58(9):1267-70. DOI:10.1248/cpb.58.1267
[2] Lee SR, et al. Constituents from Scutellaria barbata Inhibiting Nitric Oxide Production in LPS-Stimulated Microglial Cells. Chem Biodivers. 2017 Nov;14(11). DOI:10.1002/cbdv.201700231 |
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