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131311-25-6

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131311-25-6 Structure

131311-25-6 Structure
IdentificationBack Directory
[Name]

TCV 309
[CAS]

131311-25-6
[Synonyms]

TCV 309
TCV 309 int
TCV-309 int
[Molecular Formula]

C30H36BrN5O7
[MDL Number]

MFCD00894027
[MOL File]

131311-25-6.mol
[Molecular Weight]

658.54
Hazard InformationBack Directory
[Uses]

TCV-309 is an antagonist for platelet activating factor (PAF). TCV-309 improves the left ventricular function during ischemia-reperfusion (77.6% recover at 1 μM), protects the cardiac function[1].
[References]

[1] Katoh S, et al., Role of platelet activating factor in ischaemia-reperfusion injury of isolated rabbit hearts: protective effect of a specific platelet activating factor antagonist, TCV-309. Cardiovasc Res. 1993 Aug;27(8):1430-4. DOI:10.1093/cvr/27.8.1430
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