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1313407-95-2

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1313407-95-2 Structure

1313407-95-2 Structure
IdentificationBack Directory
[Name]

ARRY382
[CAS]

1313407-95-2
[Synonyms]

ARRY382
RRY-382
ARRY-382
ARRY 382,ARRY382
N-(3-cyclopropyl-1-((6-methylpyridin-2-yl)methyl)-1H-indazol-4-yl)-7-(2-(4-methylpiperazin-1-yl)ethoxy)imidazo[1,2-a]pyridine-3-carboxamide
Imidazo[1,2-a]pyridine-3-carboxamide, N-[3-cyclopropyl-1-[(6-methyl-2-pyridinyl)methyl]-1H-indazol-4-yl]-7-[2-(4-methyl-1-piperazinyl)ethoxy]-
[Molecular Formula]

C32H36N8O2
[MDL Number]

MFCD32709977
[MOL File]

1313407-95-2.mol
[Molecular Weight]

564.68
Chemical PropertiesBack Directory
[density ]

1.37±0.1 g/cm3(Predicted)
[solubility ]

Acetonitrile: Soluble
DMSO: Soluble
[form ]

Solid
[pka]

10.33±0.50(Predicted)
Hazard InformationBack Directory
[Uses]

ARRY-382 is a potent, oral and highly selective inhibitor of CSF1R/c-Fms with an IC50 of 9 nM. ARRY-382 can be used for the research of advanced or metastatic cancers[1].
[References]

[1] David K Edwards V, et al. Targeting of colony-stimulating factor 1 receptor (CSF1R) in the CLL microenvironment yields antineoplastic activity in primary patient samples. Oncotarget. 2018 May 15;9(37):24576-24589. DOI:10.18632/oncotarget.25191
Spectrum DetailBack Directory
[Spectrum Detail]

ARRY382(1313407-95-2)1HNMR
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