| Identification | Back Directory | [Name]
HG6-64-1 | [CAS]
1315329-43-1 | [Synonyms]
CS-1301
HG6-64-1
HMSL 10017-101-1
HG6-64-1
(HG 6-64-1)
Benzamide, N-[4-[(4-ethyl-1-piperazinyl)methyl]-3-(trifluoromethyl)phenyl]-3-[(1E)-2-(4-methoxy-1H-pyrrolo[2,3-b]pyridin-5-yl)ethenyl]-4-methyl- | [Molecular Formula]
C32H34F3N5O2 | [MDL Number]
MFCD28167804 | [MOL File]
1315329-43-1.mol | [Molecular Weight]
577.64 |
| Chemical Properties | Back Directory | [density ]
1.295±0.06 g/cm3(Predicted) | [storage temp. ]
4°C, protect from light, stored under nitrogen | [solubility ]
DMSO: ≥ 100 mg/mL (173.12 mM); Water: < 0.1 mg/mL (insoluble) | [form ]
Powder | [pka]
13.24±0.70(Predicted) | [color ]
Light yellow to yellow |
| Hazard Information | Back Directory | [Uses]
HG6-64-1 is a potent and selective B-Raf inhibitor extracted from patent WO 2011090738 A2, example 9 (XI-1); has a IC50 of 0.09 μM on B-raf V600E transformed Ba/F3 cells. | [Definition]
ChEBI: N-[4-[(4-ethyl-1-piperazinyl)methyl]-3-(trifluoromethyl)phenyl]-3-[2-(4-methoxy-1H-pyrrolo[2,3-b]pyridin-5-yl)ethenyl]-4-methylbenzamide is a member of benzamides. | [IC 50]
B-RafV600E: 0.09 μM (IC50, in Ba/F3 cells) | [storage]
4°C, protect from light, stored under nitrogen | [References]
[1] WO 2011090738 A2 |
|
| Company Name: |
SPIRO PHARMA
|
| Tel: |
|
| Website: |
www.spiropharma.com.cn |
| Company Name: |
Musechem
|
| Tel: |
+1-800-259-7612 |
| Website: |
www.musechem.com |
| Company Name: |
Cckinase, Inc.
|
| Tel: |
+1 (732)236-3202 |
| Website: |
www.cckinase.com |
|