| Identification | Back Directory | [Name]
4-Quinolinecarboxaldehyde, 2-(7-methoxypyrrolo[1,2-a]quinoxalin-4-yl)hydrazone | [CAS]
1315475-30-9 | [Synonyms]
PrPSc-IN-1
4-Quinolinecarboxaldehyde, 2-(7-methoxypyrrolo[1,2-a]quinoxalin-4-yl)hydrazone | [Molecular Formula]
C22H17N5O | [MDL Number]
MFCD32174059 | [MOL File]
1315475-30-9.mol | [Molecular Weight]
367.4 |
| Hazard Information | Back Directory | [Description]
PrPSc-IN-1 is a fluorescent probe, binds to the misfolded protein PrPSc, inhibits its accumulation, with an IC50 of 1.6 μM. Anti-prion activity[1].
IC50:1.6 μM (PrPSc)[1] | [Uses]
PrPSc-IN-1 is a fluorescent probe, binds to the misfolded protein PrPSc, inhibits its accumulation, with an IC50 of 1.6 μM. Anti-prion activity[1]. | [References]
[1]. Zaccagnini L, et al. Identification of novel fluorescent probes preventing PrPSc replication in prion diseases. Eur J Med Chem. 2017 Feb 15;127:859-873. |
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