| Identification | Back Directory | [Name]
1H-Pyrrole-3-carboxylic acid, 5-(4-chlorophenyl)-2-methyl-1-phenyl-, ethyl ester | [CAS]
131721-28-3 | [Synonyms]
NAP 1,NAP1
1H-Pyrrole-3-carboxylic acid, 5-(4-chlorophenyl)-2-methyl-1-phenyl-, ethyl ester | [Molecular Formula]
C20 H18 Cl N O2 | [MDL Number]
MFCD01314480 | [MOL File]
131721-28-3.mol | [Molecular Weight]
339.82 |
| Hazard Information | Back Directory | [Description]
NAP-1 is a compound with anesthetic activity. It increases paired-pulse inhibition in the CA1 region of rat hippocampal brain slices when used at a concentration of 100 μM. NAP-1 also induces loss of righting reflex in tadpoles (EC50 = 0.53 μM). | [Uses]
NAP-1 is a compound with agent that can suppress or relieve pain. effects. NAP-1 enhances the inhibitory current by binding to a specific site of GABAaR, resulting in a narcotic effect. NAP-1 can be used in research to develop clinical agent that can suppress or relieve pain[1]. | [References]
[1] Edward John BERTACCINI, et al. Novel methods, compounds, and compositions for anesthesia. WO2016061538A1. 2018-12-05 |
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