ChemicalBook--->CAS DataBase List--->131780-48-8

131780-48-8

131780-48-8 Structure

131780-48-8 Structure
IdentificationBack Directory
[Name]

DAU 5884 hydrochloride
[CAS]

131780-48-8
[Synonyms]

(1R,5S)-rel-8-Methyl-8-azabicyclo[3.2.1]octan-3-yl 2-oxo-1,2-dihydroquinazoline-3(4H)-carboxylate hydrochloride
8-Methyl-8-azabicyclo-3-endo[3.2.1]oct-3-yl-1,4-dihydro-2-oxo-3(2H)-quinazolinecarboxylic acid ester hydrochloride
[Molecular Formula]

C17H22ClN3O3
[MOL File]

131780-48-8.mol
[Molecular Weight]

351.83
Chemical PropertiesBack Directory
[storage temp. ]

Store at -20°C
[solubility ]

Soluble to 50 mM in water and to 100 mM in DMSO
[form ]

Powder
[color ]

White to off-white
Hazard InformationBack Directory
[Description]

Selective muscarinic M3 receptor antagonist. In bovine tracheal smooth muscle, inhibits methacholine-dependent effects on cell proliferation and muscle contractility.
[Uses]

DAU 5884 hydrochloride is a potent muscarinic M3 receptor antagonist. DAU 5884 hydrochloride inhibits methacholine-dependent effects on cell proliferation and muscle contractility[1].
[storage]

Desiccate at +4°C
[References]

[1] Gosens R, et, al. Muscarinic M3-receptors mediate cholinergic synergism of mitogenesis in airway smooth muscle. Am J Respir Cell Mol Biol. 2003 Feb;28(2):257-62. DOI:10.1165/rcmb.2002-0128OC
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