| Identification | Back Directory | [Name]
Rilmakalim | [CAS]
132014-21-2 | [Synonyms]
HOE 234
Rilmakalim
(3S,4R)-3-Hydroxy-2,2-dimethyl-4-(2-oxopyrrolidin-1-yl)-6-(phenylsulfonyl)chroman
1-((3S,4R)-3-Hydroxy-2,2-dimethyl-6-(phenylsulfonyl)chroman-4-yl)pyrrolidin-2-one
(3S)-3,4-Dihydro-2,2-dimethyl-4α-(2-oxo-1-pyrrolidinyl)-6-phenylsulfonyl-2H-1-benzopyran-3β-ol
2-Pyrrolidinone, 1-[(3S,4R)-3,4-dihydro-3-hydroxy-2,2-dimethyl-6-(phenylsulfonyl)-2H-1-benzopyran-4-yl]- | [Molecular Formula]
C21H23NO5S | [MDL Number]
MFCD00865817 | [MOL File]
132014-21-2.mol | [Molecular Weight]
401.48 |
| Hazard Information | Back Directory | [Uses]
Rilmakalim (HOE 234) is a potassium channel opener
(PCO) that activates ATP-sensitive K+ channels in the
heart or other tissues[1]. | [References]
[1] Kocic, Ivan
et al. Hypotonic stress increases efficacy of rilmakalim, but not pinacidil, to
activate ATP-sensitive K(+) current in guinea pig ventricular myocytes. Journal
of pharmacological sciences vol. 95,2 (2004): 189-95. DOI:10.1254/jphs.fp0030477 |
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