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132014-87-0

132014-87-0 Structure

132014-87-0 Structure
IdentificationBack Directory
[Name]

α-Methyl-γ-hydroxy-1,N2-propano-2'-deoxyguanosine (Mixture of DiastereoMers)
[CAS]

132014-87-0
[Synonyms]

α-Methyl-γ-hydroxy-1,N2-propano-2'-deoxyguanosine
α-Methyl-γ-hydroxy-1,N2-propano-2'-deoxyguanosine (Mixture of DiastereoMers)
α-Methyl-γ-hydroxy-1,N2-propano-2’-deoxyguanosine (Mixture of Diastereomers)
3-(2-Deoxy-β-D-erythro-pentofuranosyl)-4,6,7,8-tetrahydro-8-hydroxy-6-MethylpyriMido[1,2-a]purin-10(3H)-one
Pyrimido[1,2-a]purin-10(3H)-one, 3-(2-deoxy-β-D-erythro-pentofuranosyl)-4,6,7,8-tetrahydro-8-hydroxy-6-methyl-
8-hydroxy-3-(4-hydroxy-5-hydroxymethyl-tetra-hydrofuran-2-yl)-6-methyl-5,6,7,8-tetrahydro-3H-1,3,4,5,8a-pentaaza-cyclopenta[b]naphthalen-9-one
[Molecular Formula]

C14H19N5O5
[MOL File]

132014-87-0.mol
[Molecular Weight]

337.34
Chemical PropertiesBack Directory
[Melting point ]

135-137°C
[Boiling point ]

724.7±70.0 °C(Predicted)
[density ]

1.93±0.1 g/cm3(Predicted)
[storage temp. ]

Hygroscopic, -20°C Freezer, Under Inert Atmosphere
[solubility ]

Methanol (Slightly), Water (Slightly)
[form ]

Solid
[pka]

11.80±0.40(Predicted)
[color ]

White to Light Yellow
[Stability:]

Hygroscopic
Hazard InformationBack Directory
[Chemical Properties]

White Solid
[Uses]

A genotoxi crotonaldehyde.
[Uses]

A genotoxic cyclic adduct of 2''-deoxyguanosine with crotonaldehyde. Histones accelerate the cyclic 1,N2-propanoguanine adduct-formation of DNA by the primary metabolite of alcohol and carcinogenic crotonaldehyde.
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