ChemicalBook--->CAS DataBase List--->1320211-70-8

1320211-70-8

Request For Quotation
1320211-70-8 Structure

1320211-70-8 Structure
IdentificationBack Directory
[Name]

R-Pralatrexate
[CAS]

1320211-70-8
[Synonyms]

R-Pralatrexate
Pralatrexate, (R)-
L-Glutamic acid, N-[4-[(1R)-1-[(2,4-diamino-6-pteridinyl)methyl]-3-butyn-1-yl]benzoyl]-
[Molecular Formula]

C23H23N7O5
[MOL File]

1320211-70-8.mol
[Molecular Weight]

477.47
Chemical PropertiesBack Directory
[density ]

1.471±0.06 g/cm3(Predicted)
[pka]

3.53±0.10(Predicted)
Hazard InformationBack Directory
[Uses]

(R)-Pralatrexate is the (R)-enantiomer of Pralatrexate (HY-10446). Pralatrexate is an antifolate and is a potent dihydrofolate reductasean (DHFR) inhibitor[1].
[References]

[1] Enrica Marchi, et al. Pralatrexate Is Synergistic With the Proteasome Inhibitor Bortezomib in in Vitro and in Vivo Models of T-cell Lymphoid Malignancies. Clin Cancer Res. 2010 Jul 15;16(14):3648-58. DOI:10.1158/1078-0432.CCR-10-0671
1320211-70-8 suppliers list
Company Name: TargetMol Chemicals Inc.
Tel: +1-781-999-5354; +17819995354 , +17819995354
Website: https://www.targetmol.com/
Company Name: BOC Sciences  
Tel: 1-631-485-4226; 16314854226
Website: https://www.bocsci.com
Company Name: Quality Control Solutions Ltd.  
Tel: 0755-66853366 13670046396
Website: www.qcsrm.com
Company Name: BOC Sciences  
Tel: 16314854226
Website: www.bocsci.com
Company Name: Hubei Xinyang Medical Technology Co., Ltd  
Tel: 15347293736
Website: yongstandards.com/
Company Name: TargetMol Chemicals Inc.  
Tel: 4008200310
Website: https://www.targetmol.cn/
Company Name: Nantong Hanfang Biotechnology Co. , Ltd.  
Tel: hanfangpharma@126.com; 18616537568
Website: https://hanfangpharma@126.com
Company Name: TLC Pharmaceutical Standards Ltd.  
Tel: 18012923235; 18012923235
Website: http://www.tlcstandards.com
Company Name: Changzhou Xianglong Pharmaceutical Technology Co., Ltd.,  
Tel: 18915873328 18915873328
Website: www.xianglongpharm.com/
Tags:1320211-70-8 Related Product Information