| Identification | Back Directory | [Name]
[hydroxy(propan-2-yl)carbamoyl]formic acid | [CAS]
132418-03-2 | [Synonyms]
[hydroxy(propan-2-yl)carbamoyl]formic acid
Acetic acid, 2-[hydroxy(1-methylethyl)amino]-2-oxo- | [Molecular Formula]
C5H9NO4 | [MOL File]
132418-03-2.mol | [Molecular Weight]
147.13 |
| Chemical Properties | Back Directory | [Boiling point ]
297.0±23.0 °C(Predicted) | [density ]
1.362±0.06 g/cm3(Predicted) | [form ]
Solid | [pka]
5.34±0.40(Predicted) | [color ]
Off-white to light yellow |
| Hazard Information | Back Directory | [Uses]
IpOHA is a potent plant KARI inhibitor. IpOHA also is an antimycobacterial agent with a Ki value of 97.7 nM for Mycobacterium tuberculosis (Mt)[1]. | [References]
[1] Kandale A, et al. Analogues of the Herbicide, N-Hydroxy-N-isopropyloxamate, Inhibit Mycobacterium tuberculosis Ketol-Acid Reductoisomerase and Their Prodrugs Are Promising Anti-TB Drug Leads. J Med Chem. 2021 Feb 11;64(3):1670-1684. DOI:10.1021/acs.jmedchem.0c01919 |
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