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13276-53-4

13276-53-4 Structure

13276-53-4 Structure
IdentificationBack Directory
[Name]

1-(2'-deoxy-beta-threopentofuranosyl)adenine
[CAS]

13276-53-4
[Synonyms]

9-(2'-Deoxy-b-D-xylofuranosyl)adenine
1-(2'-deoxy-beta-threopentofuranosyl)adenine
9-(2-Deoxy-beta-D-threo-pentofuranosyl)adenine
9-(2-Deoxy-beta-D-threo-pentofuranosyl)adenine
9H-Purin-6-amine, 9-(2-deoxy-β-D-threo-pentofuranosyl)-
[Molecular Formula]

C10H13N5O3
[MOL File]

13276-53-4.mol
[Molecular Weight]

251.25
Chemical PropertiesBack Directory
[Boiling point ]

627.2±65.0 °C(Predicted)
[density ]

1.91±0.1 g/cm3(Predicted)
[pka]

13.79±0.60(Predicted)
Hazard InformationBack Directory
[Uses]

9-(2-Deoxy-β-D-threo-pentofuranosyl)-9H-purin-6-amine is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277)[1].
[References]

[1] Man S, et al. Potential and promising anticancer drugs from adenosine and its analogs. Drug Discov Today. 2021 Jun;26(6):1490-1500. DOI:10.1016/j.drudis.2021.02.020
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