| Identification | Back Directory | [Name]
(2-AMINO-4,5-DIMETHYL-3-THIENYL)-[3-(TRIFLUOROMETHYL)PHENYL]METHANONE | [CAS]
132861-87-1 | [Synonyms]
PD 81,723
4,5-Dimethyl-3-[3-(trifluoromethyl)benzoyl]-2-thiophenamine
(2-Amino-4,5-dimethylthiophen-3-yl)(3-trifluoromethylphenyl) ketone
(3-Trifluoromethylphenyl)(2-amino-4-methyl-5-methyl-3-thienyl) ketone
(2-AMINO-4,5-DIMETHYL-3-THIENYL)-[3-(TRIFLUOROMETHYL)PHENYL]METHANONE
Methanone, (2-aMino-4,5-diMethyl-3-thienyl)[3-(trifluoroMethyl)phenyl]-
(2-Amino-4,5-dimethylthiophen-3-yl)-(3-(trifluoromethyl)phenyl)methanone
(2-amino-4,5-dimethyl-3-thiophenyl)-[3-(trifluoromethyl)phenyl]methanone | [Molecular Formula]
C14H12F3NOS | [MDL Number]
MFCD01321053 | [MOL File]
132861-87-1.mol | [Molecular Weight]
299.31 |
| Chemical Properties | Back Directory | [Melting point ]
100-104 °C(Solv: ligroine (8032-32-4)) | [Boiling point ]
411.7±45.0 °C(Predicted) | [density ]
1.328±0.06 g/cm3(Predicted) | [storage temp. ]
Sealed in dry,2-8°C | [solubility ]
DMSO: ~13 mg/mL | [form ]
solid | [pka]
-1.36±0.13(Predicted) | [color ]
yellow |
| Hazard Information | Back Directory | [Uses]
PD 81,723 is an allosteric potentiator that increases the functional effects of adenosine and adenosine analogs. | [Biological Activity]
Allosteric potentiator at the adenosine A 1 receptor; acts via agonist-dependent and -independent mechanisms. Enhances agonist affinity for, and increased t 1/2 of dissociation from, the receptor. Also inhibits basal and forskolin-stimulated adenylyl cyclase (AC) activity in A 1 receptors expressed in CHO cells, possibly via direct potentiation of constitutive receptor activity or by direct inhibition of AC. Active in vivo . | [storage]
Store at RT |
|
| Company Name: |
BOC Sciences
|
| Tel: |
|
| Website: |
https://www.bocsci.com |
| Company Name: |
Energy Chemical
|
| Tel: |
021-58432009 400-005-6266 |
| Website: |
http://www.energy-chemical.com |
|