| Identification | Back Directory | [Name]
7-[3-[4-(2,3-dimethylphenyl)piperazin-1-yl]propoxy]-1H-quinolin-2-one:hydrochloride | [CAS]
1329509-60-5 | [Synonyms]
7-[3-[4-(2,3-dimethylphenyl)piperazin-1-yl]propoxy]-1H-quinolin-2-one:hydrochloride | [Molecular Formula]
C24H30ClN3O2 | [MOL File]
1329509-60-5.mol | [Molecular Weight]
427.967 |
| Hazard Information | Back Directory | [Uses]
OPC 4392 hydrochloride is an agonist for presynaptic dopamine receptor and an antagonist for postsynaptic D2 receptor. OPC 4392 reverses the Reserpine (HY-N0480)-induced dopamine accumulation, inhibits Apomorphine (HY-12723)-induced stereotypic and climbing behaviors in mouse models[1]. | [References]
[1] Yasuda Y, et al., 7-[3-(4-[2,3-Dimethylphenyl]piperazinyl)propoxy]-2(1H)-quinolinone (OPC-4392), a presynaptic dopamine autoreceptor agonist and postsynaptic D2 receptor antagonist. Life Sci. 1988;42(20):1941-54. DOI:10.1016/0024-3205(88)90493-6 |
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