| Identification | Back Directory | [Name]
4-ETHYLPHENYLAMINO-1,2-DIMETHYL-6-METHYLAMINOPYRIMIDINIUM CHLORIDE | [CAS]
133060-80-7 | [Synonyms]
ZD 7288
ZD7288 hydrate
ZD7288 hydrate >=98% (HPLC)
4-ETHYLPHENYLAMINO-1,2-DIMETHYL-6-METHYLAMINOPYRIMIDINIUM CHLORIDE
N-Ethyl-1,6-dihydro-1,2-dimethyl-6-(methylimino)-N-phenyl-4-Pyrimidinamine
4-(N-Ethyl-N-phenylamino)-1,2 dimethyl-6-(methylamino) pyrimidinium chloride
4-Pyrimidinamine, N-ethyl-1,6-dihydro-1,2-dimethyl-6-(methylimino)-N-phenyl- | [Molecular Formula]
C15H20N4 | [MDL Number]
MFCD29919955 | [MOL File]
133060-80-7.mol | [Molecular Weight]
256.35 |
| Chemical Properties | Back Directory | [Boiling point ]
359.9±52.0 °C(Predicted) | [density ]
1.04±0.1 g/cm3(Predicted) | [storage temp. ]
2-8°C | [solubility ]
DMSO: soluble10mg/mL, clear | [form ]
powder | [pka]
11.97±0.70(Predicted) | [color ]
white to beige |
| Hazard Information | Back Directory | [Uses]
ZD7288 hydrate has been used as?Ih?blocker to study its effect on
neocortical tissue. It has been used as hyperpolarization-activated and cyclic nucleotide-gated (HCN)-channel blocker to test the involvement of HCN channels in the phototransduction pathway. | [Biochem/physiol Actions]
Selective blocker of cation channel Ih; If blocker and sino-atrial node function modulator, blocks hyperpolarization-activated and cyclic nucleotide-gated (HCN) channels. |
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