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133060-80-7

133060-80-7 Structure

133060-80-7 Structure
IdentificationBack Directory
[Name]

4-ETHYLPHENYLAMINO-1,2-DIMETHYL-6-METHYLAMINOPYRIMIDINIUM CHLORIDE
[CAS]

133060-80-7
[Synonyms]

ZD 7288
ZD7288 hydrate
ZD7288 hydrate >=98% (HPLC)
4-ETHYLPHENYLAMINO-1,2-DIMETHYL-6-METHYLAMINOPYRIMIDINIUM CHLORIDE
N-Ethyl-1,6-dihydro-1,2-dimethyl-6-(methylimino)-N-phenyl-4-Pyrimidinamine
4-(N-Ethyl-N-phenylamino)-1,2 dimethyl-6-(methylamino) pyrimidinium chloride
4-Pyrimidinamine, N-ethyl-1,6-dihydro-1,2-dimethyl-6-(methylimino)-N-phenyl-
[Molecular Formula]

C15H20N4
[MDL Number]

MFCD29919955
[MOL File]

133060-80-7.mol
[Molecular Weight]

256.35
Chemical PropertiesBack Directory
[Boiling point ]

359.9±52.0 °C(Predicted)
[density ]

1.04±0.1 g/cm3(Predicted)
[storage temp. ]

2-8°C
[solubility ]

DMSO: soluble10mg/mL, clear
[form ]

powder
[pka]

11.97±0.70(Predicted)
[color ]

white to beige
Safety DataBack Directory
[WGK Germany ]

3
Hazard InformationBack Directory
[Uses]

ZD7288 hydrate has been used as?Ih?blocker to study its effect on
neocortical tissue. It has been used as hyperpolarization-activated and cyclic nucleotide-gated (HCN)-channel blocker to test the involvement of HCN channels in the phototransduction pathway.
[Biochem/physiol Actions]

Selective blocker of cation channel Ih; If blocker and sino-atrial node function modulator, blocks hyperpolarization-activated and cyclic nucleotide-gated (HCN) channels.
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