| Identification | Back Directory | [Name]
PGD-M | [CAS]
133161-96-3 | [Synonyms]
PGDM
TETRANOR-PGDM
TETRANOR-PROSTAGLANDIN D METABOLITE
(Z)-9α-11β-dihydroxy-15-oxo-2,3,18.19-tetranorprost-5-ene-1,20-dioic acid
Cyclopentanehexanoic acid, 2-[(2Z)-4-carboxy-2-buten-1-yl]-3,5-dihydroxy-γ-oxo-, (1R,2R,3S,5S)- | [Molecular Formula]
C16H24O7 | [MDL Number]
MFCD18432701 | [MOL File]
133161-96-3.mol | [Molecular Weight]
328.36 |
| Hazard Information | Back Directory | [Description]
Prostaglandin D2 (PGD2) plays a pharmacological role in allergic and asthmatic anaphylaxis, normal physiological sleep and lowering of body temperature, as well as inhibits platelet aggregation and relaxes vascular smooth muscle. PGDM is a major urinary metabolite of PGD2 with a unique lower sidechain that readily undergoes reversible cyclization. It is used as a biomarker to assess endogenous production of PGD2. | [Uses]
Labelled PGD-M | [Uses]
PGD-M is the major urinary metabolite of PGD2 in humans. | [Uses]
Prostaglandin D2 (PGD2) plays a pharmacological role in allergic and asthmatic anaphylaxis, normal physiological sleep and lowering of body temperature, as well as inhibits platelet aggregation and relaxes vascular smooth muscle. PGDM is a major urinary metabolite of PGD2 with a unique lower sidechain that readily undergoes reversible cyclization. It is used as a biomarker to assess endogenous production of PGD2. | [storage]
Store at -20°C | [References]
[1] H. GILES P. L. The biology and pharmacology of PGD2[J]. Prostaglandins, 1988, 35 2: Pages 277-300. DOI: 10.1016/0090-6980(88)90093-7
[2] JASON D. MORROW. Quantification of the major urinary metabolite of prostaglandin D2 by a stable isotope dilution mass spectrometric assay[J]. Analytical biochemistry, 1991, 193 1: Pages 142-148. DOI: 10.1016/0003-2697(91)90054-w |
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| Company Name: |
Energy Chemical
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021-58432009 400-005-6266 |
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http://www.energy-chemical.com |
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