| Identification | Back Directory | [Name]
Apalutamide Acid Impurity | [CAS]
1332391-04-4 | [Synonyms]
Apalutamide-COOH
Apalutamide Acid Impurity | [Molecular Formula]
C20H12F4N4O3S | [MDL Number]
MFCD33023514 | [MOL File]
1332391-04-4.mol | [Molecular Weight]
464.39 |
| Chemical Properties | Back Directory | [Boiling point ]
661.7±65.0 °C(Predicted) | [density ]
1.69±0.1 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [form ]
Solid | [pka]
2.81±0.10(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
Apalutamide-COOH is a metabolite of Apalutamide. Apalutamide is a potent and competitive androgen receptor (AR) antagonist, binding AR with an IC50 of 16 nM[1]. | [storage]
Store at -20°C | [References]
[1] Nicholas D. Smith, et al. Androgen receptor modulators and uses thereof. WO2011103202A2. |
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TOSUN PHARM
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61855200 13326451905 |
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www.toref.cn/ |
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