| Identification | Back Directory | [Name]
18 hydroxy arachidonic acid | [CAS]
133268-58-3 | [Synonyms]
(±)18-HETE
PPCHNRUZQWLEMF-XBOCNYGYSA-N
18 hydroxy arachidonic acid
18-hydroxy-5(Z),8(Z),11(Z),14(Z)-eicosatetraenoic acid
rac-(5Z,8Z,11Z,14Z)-18-hydroxyeicosa-5,8,11,14-tetraenoic acid
5,8,11,14-Eicosatetraenoic acid, 18-hydroxy-, (5Z,8Z,11Z,14Z)- | [Molecular Formula]
C20H32O3 | [MDL Number]
MFCD11045846 | [MOL File]
133268-58-3.mol | [Molecular Weight]
320.47 |
| Chemical Properties | Back Directory | [Boiling point ]
477.3±45.0 °C(Predicted) | [density ]
0.984±0.06 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
0.1 M Na2CO3: 2 mg/ml; DMF: Miscible; DMSO: Miscible; Ethanol: Miscible; PBS (pH 7.2): 0.8 mg/ml | [pka]
4.75±0.10(Predicted) |
| Hazard Information | Back Directory | [Uses]
18-HETE (compound 3) is a monooxygenase metabolite of cytochrome P450 (CYP450).18- HETE consists of arachidonic acid bearing a hydroxy substituent at position 18[1]. | [Definition]
ChEBI: A HETE that consists of arachidonic acid bearing a hydroxy substituent at position 18. | [References]
[1] Bertrand Heckmann; et al. Chiral acetals: Stereocontrolled syntheses of 16-, 17-, and 18-hydroxyeicosatetraenoic acids, cytochrome P-450 arachidonate metabolites.Tetrahedron Letters ,1996, 37(9), 1425-1428. |
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