ChemicalBook--->CAS DataBase List--->133305-88-1

133305-88-1

133305-88-1 Structure

133305-88-1 Structure
IdentificationBack Directory
[Name]

EprinoMectin B1a
[CAS]

133305-88-1
[Synonyms]

EprinoMectin B1a
Eprinomectin Component B
eprinomectin component B1a
ZKWQQXZUCOBISE-NAMFGXNGSA-N
Avermectin A1a, 4''-(acetylamino)-5-O-demethyl-4''-deoxy-, (4''R)-
[Molecular Formula]

C50H75NO14
[MDL Number]

MFCD00866565
[MOL File]

133305-88-1.mol
[Molecular Weight]

914.14
Chemical PropertiesBack Directory
[storage temp. ]

Store at -20°C
[solubility ]

DMF: soluble; DMSO: soluble; Ethanol: soluble; Methanol: soluble
[form ]

A solid
Safety DataBack Directory
[Symbol(GHS) ]

Exclamation Mark (GHS07)
GHS07
[Signal word ]

Warning
[Hazard statements ]

H319-H315
[Precautionary statements ]

P264-P280-P305+P351+P338-P337+P313P-P264-P280-P302+P352-P321-P332+P313-P362
Hazard InformationBack Directory
[Uses]

Eprinomectin B1a is a semi-synthetic analogue of avermectin B1a prepared by oxidation of the 4”-hydroxy moiety and reductive amination followed by acetylation. Eprinomectin B1a is the major component (>90%) of the commercial product for endo- and exo-parasite control, eprinomectin. Members of the avermectin/milbemycin class exert their anthelmintic effects by binding to glutamate-gated chloride channels expressed on nematode neurones and pharyngeal muscle cells. The avermectins and milbemycins are also potent insecticides and acaricides.
[Definition]

ChEBI: An avermectin analogue that is avermectin A1a in which the methoxy group attached to the tetrahydrobenzofuranyl moiety is replaced by a hydroxy group and in which the hydroxy group at position 4 of the terminal 2,6-dideoxy-3-O /element>-methyl-alpha-L-arabino-hyxopoyranosyl group is replaced by an acetamido group.
[Brand name]

Eprinex [Veterinary](Merial).
[storage]

Store at -20°C
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