ChemicalBook--->CAS DataBase List--->1333126-30-9

1333126-30-9

1333126-30-9 Structure

1333126-30-9 Structure
IdentificationBack Directory
[Name]

4’-Azido-3’-O-benzoyl-5’-O-(m-chlorobenzoyl)-2’-deoxy-2’-fluoro-beta-D-arabinouridine
[CAS]

1333126-30-9
[Synonyms]

4’-Azido-3’-O-benzoyl-5’-O-(m-chlorobenzyl)-2’-deoxy-2’-fluoro-β-Darabinouridine
4’-Azido-3’-O-benzoyl-5’-O-(m-chlorobenzoyl)-2’-deoxy-2’-fluoro-beta-D-arabinouridine
1-[4-Azido-3-O-benzoyl-5-O-(3-chlorobenzoyl)-(2-deoxy-2-fluoro-b-D-arabinofuranosyl)uracil
[Molecular Formula]

C23H17ClFN5O7
[MOL File]

1333126-30-9.mol
[Molecular Weight]

529.87
Chemical PropertiesBack Directory
[InChIKey]

ZSOIOSPOWYBGRD-MOSRZVNLNA-N
[SMILES]

C([C@]1(O[C@@H](N2C=CC(=O)NC2=O)[C@@H](F)[C@@H]1OC(C1C=CC=CC=1)=O)N=[N+]=[N-])OC(C1C=CC=C(Cl)C=1)=O |&1:1,3,12,14,r|
Hazard InformationBack Directory
[Uses]

1-[4-Azido-3-O-benzoyl-5-O-(3-chlorobenzoyl)-(2-Deoxy-2-fluoro-b-D-arabinofuranosyl)uracil is reported to be a reactant used for the preparation of 2''-deoxy-2''-fluoro-4''-azido nucleoside analogs which exhibited extremely potent anti-HIV activity against NL4-3 (wild-type), NL4-3 (K101E), and RTMDR viral strains. Also it is used for the synthesis of 4-substituted fluoronucleoside analogs for the treatment of Hepatitis B virus infection.
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