| Identification | Back Directory | [Name]
SPM VIII | [CAS]
133397-76-9 | [Synonyms]
SPM VIII
L-glycero-β-L-manno-Heptopyranosylamine, 4-deoxy-4-[[[(1-oxododecyl)amino]acetyl]amino]-N-1H-purin-6-yl- (9CI) | [Molecular Formula]
C26H43N7O7 | [MOL File]
133397-76-9.mol | [Molecular Weight]
565.66 |
| Hazard Information | Back Directory | [Description]
Spm viii is a derivative of the nucleoside antibiotic spicamycin with antitumor activity. | [Uses]
SPM VIII is a dodecanoyl analogue of spicamycin, a nucleoside antibiotic that contains fatty acids of various chain lengths. SPM VIII exhibits potent antitumor activity against the human gastric cancer SC-9 xenograft model[1]. | [References]
[1] Kamishohara M, et al. Structure-antitumor activity relationship of semi-synthetic spicamycin analogues. J Antibiot (Tokyo). 1993 Sep;46(9):1439-46. DOI:10.7164/antibiotics.46.1439 |
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