| Identification | Back Directory | [Name]
3-(1,3-Benzodioxol-5-yl)-1-(cis-3,5-dimethyl-1-piperidinyl)-3-(2-hydroxy-4,6-dimethoxyphenyl)-1-propanone | [CAS]
1334526-14-5 | [Synonyms]
(±)-ML 209
3-(1,3-Benzodioxol-5-yl)-1-(cis-3,5-dimethyl-1-piperidinyl)-3-(2-hydroxy-4,6-dimethoxyphenyl)-1-propanone | [Molecular Formula]
C25H31NO6 | [MDL Number]
MFCD30742939 | [MOL File]
1334526-14-5.mol | [Molecular Weight]
441.52 |
| Chemical Properties | Back Directory | [Boiling point ]
656.2±55.0 °C(Predicted) | [density ]
1.201±0.06 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMSO: 100 mM | [form ]
A solid | [pka]
9.07±0.45(Predicted) | [color ]
Off-white to light yellow |
| Hazard Information | Back Directory | [Uses]
(±)-ML 209 is a novel and selective RORγ antagonist, which suppresses human TH17 cell differentiation at submicromolar concentrations. (±)-ML 209 has potential to treat TH17-related autoimmune diseases. | [IC 50]
RORγ: 1.1 μM (IC50) | [storage]
Store at -20°C |
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| Company Name: |
BOC Sciences
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| Tel: |
1-631-485-4226; 16314854226 |
| Website: |
https://www.bocsci.com |
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