ChemicalBook--->CAS DataBase List--->13364-32-4

13364-32-4

13364-32-4 Structure

13364-32-4 Structure
IdentificationBack Directory
[Name]

clobenzorex
[CAS]

13364-32-4
[Synonyms]

Asenlix
Dinintel
SD271-12
Brn 2940566
clobenzorex
Clobenzorexum
5843-53-8 (Hydrochloride)
Clobenzorexum [inn-latin]
(+)-N-(o-Chlorobenzyl)-alpha-methylphenethylamine
(+)-N-[(2-Chlorophenyl)methyl]-α-methylbenzeneethanamine
BenzeneethanaMine,N-[(2-chlorophenyl)Methyl]-a-Methyl-, (aS)-
Benzeneethanamine, N-[(2-chlorophenyl)methyl]-α-methyl-, (αS)-
Benzeneethanamine, N-((2-chlorophenyl)methyl)-alpha-methyl-, (+)-
ClobenzorexQ: What is Clobenzorex Q: What is the CAS Number of Clobenzorex
[EINECS(EC#)]

236-434-4
[Molecular Formula]

C16H18ClN
[MDL Number]

MFCD00242898
[MOL File]

13364-32-4.mol
[Molecular Weight]

259.778
Chemical PropertiesBack Directory
[Boiling point ]

bp0.1 132-134°
[density ]

1.095±0.06 g/cm3(Predicted)
[pka]

8.65±0.19(Predicted)
Safety DataBack Directory
[Symbol(GHS) ]

Exclamation Mark (GHS07)
GHS07
[Signal word ]

Warning
[Hazard statements ]

H302
[Precautionary statements ]

P264-P270-P301+P312-P330-P501
[REACH Registrations]

Active
Hazard InformationBack Directory
[Originator]

Asenlix,Aventis
[Manufacturing Process]

A solution of 21.0 g (0.15 mol) of 2-chlorobenzaldehyde in 100 ml of ethanol (95%) was added to a solution of 20.5 g (0.152 mol) of D-1-phenyl-2-aminopropane in 100 ml of ethanol (95%). After standing for 15 h at room temperature, the ethanol was driven off, and the oily residue was then distilled to yield 36.2 g (94%) of D-N-(2-chlorobenzylidene)-2-amino-1- phenylpropane, boiling point 142°-146°C/0.1 mm Hg.
To the solution of 36.0 g (0.14 mol) of D-N-(2-chlorobenzylidene)-2-amino-1- phenylpropane in 200 ml of dry methanol were added, in portions, 5.3 g (0.14 mol) of sodium borohydride. The mixture was stirred for 1 h at room
temperature, and refluxed for 1 h water (100 ml) was then added and the methanol was removed in vacuo. After acidifying carefully with dilute hydrochloric acid, the solution was made alkaline by dilute sodium hydroxide, and extracted with ether. 33.0 g (90%) of D-N-(1-phenyl-2-propyl)-2-
chlorobenzylamine, boiling point 132°-134°C/0.1 mm Hg, were obtained by distillation.
[Brand name]

Finedal.
[Therapeutic Function]

Anorexic
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