ChemicalBook--->CAS DataBase List--->133943-59-6

133943-59-6

133943-59-6 Structure

133943-59-6 Structure
IdentificationBack Directory
[Name]

H-LEU-ARG-PRO-OH
[CAS]

133943-59-6
[Synonyms]

LRP
Leu-Arg-Pro
H-LEU-ARG-PRO-OH
LHRH 7-9 SEQUENCE
Leucylarginylproline
H-LEU-ARG-PRO-OH 2HCL
LHRH (7-9) SEQUENCE 2HCL
L-Proline,L-leucyl-L-arginyl-
[Molecular Formula]

C17H32N6O4
[MDL Number]

MFCD00190940
[MOL File]

133943-59-6.mol
[Molecular Weight]

384.47
Chemical PropertiesBack Directory
[density ]

1.39±0.1 g/cm3(Predicted)
[storage temp. ]

-15°C
[solubility ]

Soluble in DMSO
[pka]

3.39±0.20(Predicted)
[Sequence]

Leu-Arg-Pro
Hazard InformationBack Directory
[Uses]

Leucylarginylproline is an angiotensin-converting enzyme (ACE) inhibitor with an IC50 of 0.27μM.
[References]

[1] Miyoshi S, et al. Structures and activity of angiotensin-converting enzyme inhibitors in an alpha-zein hydrolysate. Agric Biol Chem. 1991 May;55(5):1313-8. PMID:1368684
[2] Chen TL, et al. Microencapsulation and modification of synthetic peptides of food proteins reduces the blood pressure of spontaneously hypertensive rats. J Agric Food Chem. 2003 Mar 12;51(6):1671-5. DOI:10.1021/jf020900u
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