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134439-56-8

134439-56-8 Structure

134439-56-8 Structure
IdentificationBack Directory
[Name]

1,3-bis(N-(N-(2-aminoethyl)-2-aminoethyl)-2-aminoacetamido)-2-(4-isothiocyanatobenzyl)propane-N,N,N',N'',N''',N'''',N''''',N'''''-octaaceticacid
[CAS]

134439-56-8
[Synonyms]

3,6,9,12,16,19,22,25-Octaazaheptacosanedioic acid, 3,6,9,19,22,25-hexakis(carboxymethyl)-14-[(4-isothiocyanatophenyl)methyl]-11,17-dioxo-
1,3-bis(N-(N-(2-aminoethyl)-2-aminoethyl)-2-aminoacetamido)-2-(4-isothiocyanatobenzyl)propane-N,N,N',N'',N''',N'''',N''''',N'''''-octaaceticacid
[Molecular Formula]

C39H57N9O18S
[MOL File]

134439-56-8.mol
[Molecular Weight]

971.98
Hazard InformationBack Directory
[Description]

LiLo is a chelating agent for attaching indium-111 to monoclonal antibodies.
[Uses]

LiLo is a new bifunctional chelator that has the activity of forming kinetically stable chelates with metal ions (such as indium). After using LiLo to bind indium-111 to monoclonal antibodies, the in vitro stability and in vivo biodistribution of the conjugates are superior to those using other chelators.
[References]

[1] New chelating agent for attaching indium-111 to monoclonal antibodies: in vitro and in vivo evaluation
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