| Identification | Back Directory | [Name]
GE 2270 A | [CAS]
134861-34-0 | [Synonyms]
GE 2270 A
9H,16H-8,5:15,12:22,19:32,29:36,33-Pentanitrilo-5H,29H,33H-pyrido[3,2-a1][1,11,18,25,31,4,7,14,21]pentathiatetraazacyclotetratriacontine-11-acetamide, 2-[4-[(4S)-4-[[(2S)-2-(aminocarbonyl)-1-pyrrolidinyl]carbonyl]-4,5-dihydro-2-oxazolyl]-2-thiazolyl]-10,11,17,18,23,24,25,26,27,28-decahydro-28-[(S)-h... | [Molecular Formula]
C56H55N15O10S6 | [MOL File]
134861-34-0.mol | [Molecular Weight]
1290.51 |
| Hazard Information | Back Directory | [Uses]
GE 2270A (MDL 62879) is an antibiotic. GE 2270A inhibits gram-positive bacteria and anaerobes by inhibiting protein synthesis. GE 2270A can be used for the research of infection[1][2]. | [References]
[1] Landini P, B et al. Inhibition of bacterial protein synthesis by elongation-factor-Tu-binding antibiotics MDL 62,879 and efrotomycin. Biochem J. 1992 May 1;283 ( Pt 3)(Pt 3):649-52. DOI:10.1042/bj2830649
[2] Anborgh PH, Parmeggiani A. New antibiotic that acts specifically on the GTP-bound form of elongation factor Tu. EMBO J. 1991 Apr;10(4):779-84. DOI:10.1002/j.1460-2075.1991.tb08009.x |
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